Assessment of Myocardial Reactivity to Controlled Hypercapnia with Free-breathing T2-prepared Cardiac Blood Oxygen Level–Dependent MR Imaging
Hsin-Jung Yang, Roya Yumul, Richard Tang, Ivan Cokic, Michael Klein, Avinash Kali, Olivia Sobczyk, Behzad Sharif, Jun Tang, Xiaoming Bi, Sotirios A. Tsaftaris, Debiao Li, Antonio Hernandez Conte, Joseph A. Fisher, Rohan Dharmakumar.
Cardiac stress testing is the standard of care for diagnosing ischemic heart disease (1). It is performed in nearly 10 million patients each year in the United States alone. It is conventionally initiated with exercise to induce hyperemia, and it is coupled with imaging to identify stress-induced failure to increase perfusion, or frank hypoperfusion in myocardial territories.